Metabolic syndrome in patients who have been subjected to isolation security measures and treated with atypical antipsychotics. / Zespól metaboliczny u pacjentów realizujacych izolacyjny srodek zabezpieczajacy, leczonych atypowymi lekami przeciwpsychotycznymi.

OBJECTIVES: The main aim of the study was to assess the incidence of metabolic syndrome and its individual components in patients subject to a confinement measure, treated with antipsychotics in mono - or polytherapy. Additional objectives included the analysis of associations between the occurrence of metabolic syndrome and patients' age, psychiatric diagnosis, overweight or obesity, and the presence of addictions to psychoactive substances. METHODS: The study involved 61 patients of the Department of Forensic Psychiatry, including 9 women and 52 men, subject to a confinement measure from September 2019 to August 2021. All parameters of metabolic syndrome and BMI were measured twice, at the beginning of the stay at the Department and after six months of treatment with atypical antipsychotics. Appropriate statistical comparative analyses were then performed. RESULTS: There was no relationship between the occurrence of metabolic syndrome and the age of the subjects, medical diagnosis, addiction to psychoactive substances, including smoking. It has not been confirmed that the chronic use of atypical antipsychotics with parallel prophylactic and health-promoting effects in conditions of confinement leads to the development of metabolic syndrome and worsens its symptoms, apart from a marked increase in waist circumference and an increase in BMI. CONCLUSIONS: Systematic measurements of BMI and waist circumference during treatment with atypical antipsychotics may be accurate tools in assessing the risk of metabolic syndrome. Long-term confinement hospitalizations should include psychoeducational nterventions aimed at minimizing metabolic complications of pharmacotherapy.

Psychological factors of aggressive behaviour in patients of forensic psychiatry wards with the diagnosis of schizophrenia.

Scientific research shows that the likelihood of aggressive behaviour in people with mental disorders compared to healthy people is usually higher than among healthy people. Considering the social harmfulness of acts committed by persons suffering from schizophrenia, a thorough analysis of their conditions is recommended. The paper presents the results of research conducted by a team from the Forensic Psychiatry Clinic of the Institute of Psychiatry and Neurology (IPiN) in Warsaw regarding the psychological determinants of aggressive behaviour of people diagnosed with schizophrenia. The analysis covers selected demographic variables, personality traits as well as the level and type of aggression presented, including previously undertaken violent behaviour. This article includes the results of studies on patients diagnosed with schizophrenia, interned in the Forensic Psychiatry Clinic of IPiN, as well as patients with schizophrenia (addicted and non-addicted) staying in general psychiatric wards.